I still don’t understand whether I can use Ingaron during every case of cold.
Ingaron is used for both treatment and preventive care of flu and ARVI. To avoid being struck with cold, you should use Ingaron as a preventive care during inter-season, and if you are already ill, you should use it for treatment during every cold, on any stage of the disease.
 I plan going on a vacation to a warm county. Should I use Ingaron as a preventive care?
You certainly should. Ingaron is recommended as a preventive care during inter-season, in cases of exposure to cold and changes in climatic temperatures, changes in diet, regimen, vitamin deficiency and changes of climatic zones. According to clinical trials, Ingaron has proved itself as a very effective preventive medicine, that can reduce the risk of infection by 2.2 times.
 My mother started treatment with Ingaron on the early stages of her cold. On the second day of treatment, her pressure rose (she’s hypertensive). Should we proceed with the treatment?
Ingaron has no effect on pressure swings. Due to having no side effects, it is good for the elderly who usually have a number of concurrent diseases. You should proceed with the treatment.
 Can I dissolve lyophilisate with a mixture of water and naphazoline in the event when my nose is blocked, and I do need easy breathing? Or do I necessarily need to rinse my nose?
Lyophilisate can only be dissolved with water (for injections), the vasoconstrictive medicine should be used separately, but no longer than during 10 days, otherwise a resistance is formed. You should rinse your nose before using the medicine.
 Can one use Ingaron along with antibiotics? Or one should better wait?
Ingaron has a wide-spectrum antiviral and antimicrobial effect; it also regulates immune reaction, activates cellular immunity, enables antiviral, antitumor and antiparasitic protection. This means that if your physician prescribed you antibiotics, you can and should combine them with Ingaron, because it amplifies their effectiveness.
 Please tell, how often can one use Ingaron? I took a course three weeks ago when I was feeling bad. Now it’s a start of flu epidemic. Can I use it again? If not, then when can I repeat the course? Can I use Ingaron (drops) in presence of nodes in the thyroid gland?
Ingaron can be used so far as necessary: during inter-season, when contacting the infected, during flu epidemics or seasons of cold-related diseases, as well as when the body is weakened, for example, when changing climatic zones or in case of exposure to cold or high loads.
During epidemics of flu or seasons of cold-related diseases, you can repeat the course as a preventive care therapy. There are no side effects reported; it can be used in presence of nodes in the thyroid gland (injectable Ingaron is even used in treatment of oncological diseases), though you should still consult your physician.
 Is it reasonable to use Ingaron along with Ingavirin?
Ingaron is compatible with all medicines, including Ingavirin. You should consult your physician about the reasonability of using both Ingaron and Ingavirin, since they both have an antiviral effect. But Ingaron has a greater antiviral effect, has a powerful stimulating effect on the immunity and, unlike granules (Ingavirin comes in granules), does not have a negative effect on gastrointestinal tract and acts immediately because it is supplied in nasal drops. After coming in contact with the nasal mucosa, it starts acting immediately.  
 My husband instilled (in streamlets) more than 2 drops of Ingaron into his nose. Will there be an overdose? Is an overdose possible at all?
According to clinical studies of Ingaron, there are no side effects, including the cases of an overdose.
 How long does the effect of preventive therapy last?
It all depends on the condition of your immune system. Interferons accumulated in one’s body do not have a “shelf life”, but there can be a deficiency of them. Interferon gamma has an ability to accumulate – if you are healthy, the excess of interferon gamma is “swallowed” by cells, and a “depot” is formed. When required (during disease or contacts with an infected), it is released into the lumen of bronchi or trachea, thus contributing to the body defense. According to the data from clinical trials, the morbidity of flu and ARVI among patients who received preventive care with Ingaron (in comparison with patients not receiving it), was 2.1 times lower during the administration month and by 1.9 times during the following month. Apart from the outbreaks of the flu epidemics and the seasons of cold-related diseases, our immunity can weaken due to other unfavorable circumstances. Thus, Ingaron is recommended in the following cases:

  • During epidemic of flu or season of cold-related diseases;
  • Contact with an infected;
  • Inter-season;
  • Cold/heat exposure;
  • Solar or thermic fever;
  • A change of climatic zones (e.g., vacation);
  • A change in diet, regimen;
  • Postoperative period;
If after a course of preventive care you have a close contact with an infected (for instance, a member of your family or a colleague fell ill), you should repeat the course.
 Does intranasal Ingaron retain its properties if it has not been stored in the fridge for 3 weeks?
If the vial has not been opened and the temperature is not higher than 25 degrees C, then the medicine retains its properties for 2 years. If you have opened and dissolved the medicine, you can store it in the fridge only for no more than 10 days.
 I have been storing the solution under room temperature for three days – not having read the storage requirements. Please tell whether the solution has lost its properties and I need to replace it with a new one or I can start storing it in the fridge and continue the treatment using this solution? And how effective was my treatment during the last three days?
After you’ve dissolved the medicine it should be only stored in the fridge. You should replace your solution with a new one, because it has lost its pharmacological properties and it won’t be effective unless its storage requirements are met.
 The price for the medicine differ depending on the content of an IE. The higher it is, the more expensive the medicine is. What’s an IE? Does this mean that the more expensive medicine is more effective?
IE is an international unit. In pharmacology, it is a dosage unit of the active substance, which defines its concentration. Ingaron comes in two forms (that differ in price):
  1. Intranasal (nasal drops) – 100 000 IE used for treatment of flu and ARVI and as a preventive care. It is available over the counter.
  2. Injectable (shots) – 100 000 IE and 500 000 IE, used for treatment of herpes virus infections, shingles, urogenital chlamydiosis, oncological diseases, chronic viral hepatitis B and C, HIV/AIDS and pulmonary tuberculosis. It has to be prescribed by a physician.
 Can a nursing mother take Ingaron? Won’t it be harmful for the baby?
There are no clinical trials of Ingaron on such groups as pregnant women or children below 7 years old, so a nursing mother should refrain from using Ingaron or consult her physician.
 Can a 13-year old teenager take Ingavirin together with Ingaron as a preventive therapy?
Yes, they can. Ingaron can be used along with any medicine, including Ingavirin.
 Please tell whether lesser doses of Ingaron can be used in a child of 5 years old, if not, what can it be replaced with?
There are no clinical trials of Ingaron on children below 7 years old, that is why it is contraindicated in children below 7 years old. As for what can it be replaced with, consult your physician.
 What is the difference between interferon alpha, beta and gamma?
Our immunity has several levels of defense: the first is associated with innate immunity, the second is associated with acquired immunity. The first level is based on production of type 1 interferons (alpha and beta). Interferons alpha and beta ensure the body protection on the early stages of the disease.
But in the event of a powerful viral attack, when the immunity is being suppressed, it becomes evident that the “breakthrough” on one level of immunity can be compensated by the activation of another.
The second level of defense is associated with the production of type 2 interferon - interferon-gamma, also called the immune interferon, because it can only be released by the cells of the immune system. It activates the body immune defense: it regulates the immune reaction, activates the cellular immunity, activates not only the innate immunity, but acquired immunity as well, and contributes to the secondary immunity, thus raising the body resistance to secondary infection. Interferon gamma plays an important role in preventing the infection development.
 Accidentally, Grandmother instilled 2 drops of INGARON per nostril to her grandchild (2 years old). We rinsed it with water, but we are still worried. Please tell us what to do.
Don’t worry. There is nothing to be afraid of. Interferon gamma is a natural protein that is produced by the human body. Contraindications state that children below 7 years old should not use it, but the reason is that there are no clinical trials on younger children.

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